Using cannabis may cause changes in the human body's epigenome, a study of over 1,000 adults suggests. The epigenome functions like a set of instructions that tells our genes when to turn on or off, ultimately influencing our health and development. By studying changes in DNA methylation, the biological process by which methyl groups are added to DNA molecules, thereby altering gene expression, researchers have discovered a potential link between cannabis use and epigenetic changes.
Marijuana is a widely used psychoactive substance in the US, and medical and recreational legalization has risen over the past decade. With increased access to cannabis, researchers are now able to study its effects on the human body more extensively. Cannabis use, both recent and long-term, has been linked to epigenetic changes in a new study. The researchers found evidence that the drug can have lasting impacts on gene expression, potentially leading to long-term health consequences.
Research indicates smoking's prolonged influence on immunity, linked to epigenetic changes, persists even after quitting. This suggests that the effects of cannabis use on the epigenome may not be fully reversible, highlighting the importance of understanding these long-term implications. OHSU researchers warn of potential impacts on brain development and long-term health related to prenatal cannabis exposure, emphasizing the need for further research in this area.